The 49ers star running back was ruled out of Sunday Night Football after suffering a knee injury in the first half against ...

The NFL world was at a loss for words after San Francisco 49ers star Christian McCaffrey fell victim to another serious ...

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...

Injuries continue to mount around the NFL, and with Thanksgiving in the rearview mirror — and playoff berths already clinched ...

San Francisco 49ers’ Christian McCaffrey is one of the most exciting talents in NFL. While his professional accomplishments ...

San Francisco enters Week 14 with a 5-7 record. The 49ers return to the Bay for a two-game homestand that includes a quick ...

San Francisco 49ers’ Christian McCaffrey is one of the most exciting talents in NFL. While his professional accomplishments ...

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Trevor Lawrence, Christian McCaffrey and Taysom Hill were among key players injured in Week 13 of the NFL season.

The San Francisco 49ers clearly struggled to adapt to the weather in Buffalo on Sunday night, and it showed, as the Bills ...

The San Francisco 49ers running back has sustained a posterior cruciate ligament (PCL) injury, head coach Kyle Shanahan ...