San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Friday's practice as the team prepares for its Week ...

The San Francisco 49ers announced Friday that they have waived wide receiver Ronnie Bell ahead of their Sunday night game ...

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

San Francisco 49ers general manager John Lynch appeared on Bay Area radio station KNBR on Friday morning to share the latest ...

The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

The San Francisco 49ers are encouraged by linebacker Dre Greenlaw's progress as he works his way back from a torn Achilles ...

The 49ers are set to have quarterback Brock Purdy back in the lineup this weekend. Purdy missed last Sunday's loss to the ...

Heavy, lake-effect snow will fall on Buffalo this weekend as the 49ers arrive to face the Bills on Sunday night in the suburb ...

Brock Purdy is expected to return Sunday night against the Bills, but offensive tackle Trent Williams, defensive end Nick ...

San Francisco 49ers quarterback Brock Purdy underwent an MRI early last week after sustaining a shoulder injury in the team's ...

The San Francisco 49ers announced the signing of offensive lineman Sebastian Gutierrez to the practice squad. To make room on ...

The San Francisco 49ers are set to visit Highmark Stadium this weekend for a critical Week 13 showdown against the Buffalo ...