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precisionmedicineonline
4 天
Adaptive Biotechnologies' MRD Test May Allow Some Mantle Cell Lymphoma Patients to Skip ...
A stem cell transplant added to Rituxan did not improve survival for MRD-negative MCL patients in their first remission ...
precisionmedicineonline
5 天
UCLA, University College London Advancing Immune Disorder Gene Therapy Toward FDA Submission
Researchers founded Rarity PBC as a public benefit corporation that will license the IP and develop operations to potentially ...
precisionmedicineonline
5 天
Genetic Variant in South American Indigenous Population Linked to Better Blood Cancer Drug ...
The variant, present in the NFKB1 gene and common in the Aymara community, could help guide treatment decisions, researchers ...
precisionmedicineonline
4 天
Risk-Reducing Surgery Improves Outcomes for Young Patients With BRCA1/2-Mutant Breast Cancer
SAN ANTONIO – In a global study involving more than 5,000 women, risk-reducing surgeries significantly improved survival and ...
precisionmedicineonline
6 天
HER2 Biomarker Evolving as Enhertu Shows Activity in Breast Cancers With Ultralow Expression
The new HER2-low category is exposing the limitations of IHC testing, challenging pathologists, and has oncologists ...
precisionmedicineonline
4 天
ASH24 Gene Therapy Readouts in Sickle Cell, TDT: Editas, Vertex, Beam, Bluebird Bio
Researchers at the meeting reported on long-term activity of commercialized gene therapies and preliminary data on ...
precisionmedicineonline
2 天
Boundless Bio Ends Trial of BBI-825 in Patients With Certain Cancer Resistance Mutations
Due to unfavorable pharmacokinetics and the development costs of BRAF V600E and KRAS G12C mutated cancers, the firm will not advance the STARMAP trial.
precisionmedicineonline
6 天
Israeli Oncologists Show Point-of-Care CAR T-Cells Have Comparable Efficacy to Yescarta ...
Lymphoma patients better tolerated the CAR T-cell therapy manufactured on site at the Sheba Medical Center than they did the ...
precisionmedicineonline
6 天
Bluebird Bio's Lyfgenia Eliminates Painful Sickle Cell Episodes Through 18 Months
In particular, patients who had fewer than 10 annual vaso-occlusive events before the gene therapy were more likely to have ...
precisionmedicineonline
2 天
Editas Medicine Lays off 65 Percent of Workforce; Drops Sickle Cell, TDT Candidate Reni-Cel
Editas, which was unable to identify a development or licensing partner for reni-cel, is focusing its resources on its in vivo pipeline.
precisionmedicineonline
4 天
Phase II Data Bode Well for Gilead Sciences, Arcellx's Multiple Myeloma CAR T-Cell Therapy
SAN DIEGO – Gilead Sciences and Arcellx's autologous B-cell maturation antigen (BCMA)-directed CAR T-cell therapy ...
precisionmedicineonline
2 天
Next-Generation Drugs Show Benefits of More Specific PI3Kα Inhibition at SABCS
First-in-human results for three investigational inhibitors show anti-tumor activity without unmanageable effects on blood glucose.
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