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Targeted Oncology
45 分钟
Luspatercept and ESAs Improve Efficacy in VEXAS Syndrome With/Without MDS
Erythropoietin stimulating agents and/or luspatercept showed positive clinical efficacy and safety in patients with VEXAS ...
Targeted Oncology
16 小时
Navtemadlin Monotherapy Shows Safety, Efficacy in R/R Myelofibrosis
Findings from the BOREAS study showed that navtemadlin as a monotherapy led to safety and efficacy in patients with ...
Targeted Oncology
19 小时
Palbociclib Combo Shows Benefit to PFS in HR+, HER2+ Breast Cancer
Progression-free survival was superior with first-line maintenance of palbociclib in HR-positive, HER2-positive metastatic ...
Targeted Oncology
22 小时
Kaklamani on Elacestrant for CDK4/6 Inhibitor-Naive ER+ Breast Cancer Treatment
Virginia G. Kaklamani, MD, DSc, discusses how effective elacestrant (Orserdu) is in CDK4/6 inhibitor-naive estrogen ...
Targeted Oncology
22 小时
Brexu-cel Shows Comparable Efficacy in Patients With B-ALL Aged 60-69
Brexucabtagene autoleucel showed comparable efficacy outcomes in patients aged 60 to 69 with relapsed/refractory B-cell acute ...
Targeted Oncology
1 天
No OS Difference Among First-Line CDK4/6 Inhibitors in HR+/HER2- mBC
A study of 9,146 patients found no OS difference among first-line CDK4/6 inhibitor combinations for HR+/HER2- metastatic ...
Targeted Oncology
23 年
MonumenTAL-1: Data Updates of Talquetamab, a GPRC5D-Directed Bispecific Antibody for RRMM
Panelist discusses how the MonumenTAL-1 study led to the approval of talquetamab in patients with 4 or more prior lines of ...
Targeted Oncology
1 天
Lower Cardiac Risks Found With Second-Generation BTK Inhibitors in B-Cell Hematologic Disorders
In a meta-analysis, second-generation BTK inhibitors were linked to a significantly low incidence of atrial fibrillation, ...
Targeted Oncology
23 年
Talquetamab Step-Up Dosing Strategies and CRS Monitoring
Panelist discusses how talquetamab’s step-up dosing strategy aims to mitigate cytokine release syndrome, a common immunologic toxicity. The reported grade 1 CRS with altered taste and dry mouth ...
Targeted Oncology
1 天
Phase 2 Trial Highlights 100% Complete Response with Cilta-Cel in Smoldering Myeloma
Ciltacabtagene autoleucel achieved a 100% complete response rate in patients with high-risk smoldering multiple myeloma, as ...
Targeted Oncology
1 天
Ten-Year Retrospective Trial of Ponatinib in Leukemia Sheds Light on AE Mitigation Efforts
Adverse events associated with ponatinib in CML and ALL were shown to have decreased significantly since its approval, ...
Targeted Oncology
1 天
Neoadjuvant SHR-A1811 Demonstrates Efficacy, Safety in HER2+ Breast Cancer
SHR-A1811 showed promising antitumor activity and acceptable tolerability in patients with HER2-positive breast cancer, ...
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