Two sides stuck on losing streaks meet at the Levi's Stadium in Game Week 14.  The Buffalo Bills comfortably beat the 49ers ...

SportsLine's model simulated the San Francisco 49ers vs. Los Angeles Rams on Thursday Night Football 10,000 times and ...

Oddsmakers project a close game when the San Francisco 49ers (6-7) host the Los Angeles Rams (7-6) on Thursday, December 12, ...

Fantasy millionaire Mike McClure shares his top NFL DFS picks for Los Angeles Rams vs. San Francisco 49ers on TNF ...

The Los Angeles Rams versus the San Francisco 49ers is one of many strong options on the Week 15 NFL schedule. With Week 15 in the ...

The San Francisco 49ers are in action on Sunday at 4:25 p.m. ET versus the Chicago Bears at Levi’s Stadium.The 49ers are ...

Los Angeles Rams @ San Francisco 49ers is Thursday's NFL game and Matt Temple-Marsh has two selections at 6/4 and bigger.

The Los Angeles Rams and San Francisco 49ers are set to square off in a crucial NFC West matchup on Thursday night, live on ...

Already missing five starters during the blowout loss to the Bills, San Francisco lost star running back Christian McCaffrey ...

The 49ers have been decimated by injuries on both sides of the football. Their chances of making a fourth-straight NFC ...

SportsLine's model simulated Chicago Bears vs. San Francisco 49ers 10,000 times and made its Week 14 NFL picks, predictions ...

Week 15 begins with an NFC West showdown between the San Francisco 49ers (-2.5, 48.5) and Los Angeles Rams at 8:15 p.m. ET on Thursday Night ...