The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

Sunday after the 49ers lost their seventh game, I asked Brock Purdy to make of the terrible season the 49ers are having. Here ...

San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach ...

The 49ers just lost their second game in a row by at least 25 points for the first time since Jim Tomsula was the head coach.

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the ...

The San Francisco 49ers will be without their top two running backs for the remainder of the regular season after the pair of ...

Christian McCaffrey’s initial diagnosis was correct. The San Francisco 49ers running back injured the PCL in his knee, an MRI ...

A Bills equipment cart awkwardly interrupted an NBC Sports Bay Area live segment after the 49ers' loss in Buffalo.

San Francisco 49ers offensive tackle Trent Williams and his wife, Sondra Williams, have issued a heartbreaking statement at ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

San Francisco 49ers player Trent Williams and his wife Sondra are mourning the passing of their newborn son, the couple ...