Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...

In laboratory experiments, doctoral students Tobias Bexte and Nawid Albinger succeeded in completely switching off an important immune checkpoint in NK cells that were specifically directed ...

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build ...

Both anti-CD19 PB-CAR-NK and PB-NK cells were co-cultured with CD19+ Nalm6 target cells (E: T = 1:1) in the presence of four factor-specific antibodies or an IgG control, and cytotoxicity was measured ...

The integration of clinical data and single-cell analyses highlights NK cell exhaustion as a key factor, offering insights with potential therapeutic implications. The work will be of interest to ...

12 月 11 日，中国科学技术大学生命科学与医学部、免疫应答与免疫治疗重点实验室王毅课题组在 Cell Reports Physical Science 在线发表了一篇题为“ A heparanase-specific LYTAC degrader reinforces natural killer cell cytotoxicity within tumor microenvironment ...

The underlying mechanisms linking ATP7B mutations to cholecystitis and natural killer cell exhaustion remain unclear. Specifically, it is not yet determined whether copper metabolism alterations ...

4Research Unit of NK Cell Study, Chinese Academy of Medical Sciences, Beijing, China. Search for other works by this author on: 1Biomedical Sciences and Health Laboratory of Anhui Province, Division ...