The role of Sirt1 was evaluated in bleomycin-induced skin fibrosis and in mice overexpressing a constitutively active transforming growth fac­tor-β (TGF-β) receptor I (TBRIact). Results The expression ...

Institute of Biology and Experimental Medicine, National Council for Scientific and Technical Research, Buenos Aires, Argentina. Research Center of Biomedical Biotechnology, Environmental and ...

The aim of this study was to investigate the expression and function of BMP6 in chronic liver disease. Design BMP6 was analysed in hepatic samples from murine models of chronic liver injury and ...

Thus far, many groups have been working in the study of serum protein changes during the development of liver fibrosis ... evaluate differences in protein expression between HCV-cirrhotic ...

Numerous literatures have reported that TREM2 can promote anti-inflammation and anti-fibrosis through inhibiting the TLRs signaling pathway, promoting phagocytosis, and inhibiting the NLRP3 ...

and affects the severity of fibrosis in CHC. However, the relationship between hepatic steatosis and chronic hepatitis B (CHB) is unclear. The aims of this study were to investigate the frequency ...

The molecular mechanisms of HSP47 induction in intestinal fibrosis related to CD, however, remain unclear. Here we investigated the role of interleukin (IL)-17A-induced HSP47 expression in intestinal ...

Math Parser: Java, C#, C++, Kotlin, Android, and all .NET platforms (Nuget, Maven, CMake). Supports .NET Framework, .NET Core, .NET Standard, Xamarin, and more ...

Itgbl1 is identified as a key factor in Acta2 high-expressing myofibroblasts, where it promotes collagen fibril formation and scarring. IL1β inhibits Itgbl1 expression and myofibroblast ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Additionally, some viruses, like hepatitis B virus (HBV), utilize protective mechanisms to shield their DNA ... Mice lacking STING show reduced expression of fibrosis markers such as αSMA, TGF-β1, and ...

Gene expression profiling is the determination of the pattern of genes expressed, at the level of transcription, under specific circumstances or in a specific cell to give a global picture of ...