With their top two options sidelined, the expectation was that rookie Isaac Guerendo would lead the backfield for the ...

The 49ers are playing on "Thursday Night Football" against the Rams. Will running back Isaac Guerendo be ready to play after ...

The San Francisco 49ers’ Week 15 injury report inspired a little bit of optimism on the health front as they enter a virtual ...

The San Francisco 49ers will face the Los Angeles Rams in Week 15. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, especially regarding ...

The San Francisco 49ers running back room is currently decimated by injuries. Superstar Christian McCaffrey (knee) sustained ...

The San Francisco 49ers released their latest injury updates headed into the team's Week 15 "Thursday Night Football" matchup ...

Status in question for Thursday ...

Welcome to Week 15 of the NFL season, a week that is synonymous with the start of Fantasy football postseasons. Fortunately for you, we've got a rundown of every team's injury report so you know who ...

Stafford is arguably the best quarterback in the NFL when he can operate from a clean pocket — he’s thrown for 2,656 yards ...

Here's the latest injury news on Derek Carr, Drew Lock and Isaac Guerendo and entering Week 15 of the NFL season.

The San Francisco 49ers defeated the Chicago Bears 38-13 last weekend at Levi’s Stadium, putting them back in the winning column for the first time since they beat the Tampa Bay Buccaneers in Week 10.

Fantasy football analyst Scott Pianowski highlights the best (and worst) playoff schedules for receivers around the league.