The Bills (10-2) ended up winning in a rout in a 35-10 final over the 49ers (5-7). That was just the start of it. On a ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

The Bills and the San Francisco 49ers went head-to-head in freezing conditions Sunday, with Bills fans and staff digging out ...

In Sunday's 35-10 win over the San Francisco 49ers, The Buffalo Bills used Alec Anderson as a third tackle on 17 plays, and ...

In a 35-10 win over the San Francisco 49ers at home in Orchard Park, HC Sean McDermott's record coming out of the bye week ...

Quarterback Josh Allen and coach Sean McDermott deserve credit in overcoming lowered expectations in leading the Buffalo ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

Buffalo Bills fans embraced the snowy conditions at Highmark Stadium in Orchard Park, New York, on December 1, as their team ...

The 49ers' playoff hopes are essentially dead now, and it became that way once McCaffrey went down with an unknown injury. On ...

A Buffalo Bills fan tried to knock down Jake Moody's field goal attempt in the 49ers' snow-filled game tonight.

Josh Allen’s memorable week began with singer and actress Hailey Steinfeld accepting his proposal for marriage and ended with ...