Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFC West. Here are their grades for this per ...

The Buffalo Bills clinched another AFC East title with a dominant 35-10 win over the San Francisco 49ers; Josh Allen had ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...

Fantasy football analyst Matt Harmon delivers his thoughts on the major happenings of Week 13's Sunday action.

Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

The San Francisco 49ers are reeling. They've lost two straight games to fall to 5-6 and under .500 for the fourth time this ...

Buffalo (9-2) brings a six-game winning streak into a matchup with San Francisco (5-6) on Sunday, December 1, 2024 at ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

Ahead of their game against the Buffalo Bills, it’s time to release our San Francisco 49ers Week 13 predictions.

How thorough was the Buffalo Bills’ 35-10 win over the San Francisco 49ers on Sunday night? Quarterback Josh Allen was ...