Toll-like receptors (TLRs) are vital components of the immune system, acting as sentinels that detect and respond to ...

The Structural and Functional Diversity of Peptides Studies suggest that peptides may exhibit remarkable diversity in structure and function, which arises from variations in amino acid composition, ...

As GLP-1 RA use soars, experts are worried that patients may not be getting the right nutrients in their diets. How can ...

Interesting targets for peptide vaccination have been defined including Wilms tumor gene 1, proteinase-3 and receptor for hyaluronan-mediated motility. The clinical angle focuses on the ...

G protein-coupled receptors (GPCRs), crucial for diverse physiological responses, have traditionally been investigated in ...

Maridebart cafraglutide, a novel injectable GLP-1 receptor agonist/GIP receptor antagonist, reduced body weight by up to ...

In a recent Perspective in Nature Immunology 1, Blander and Medzhitov explored the function of Toll-like receptor (TLR) signaling in ... generation of bacterial peptides to be presented to ...

RA was well tolerated in the Phase I trial. Now MBX is planning a Phase II trial in post-bariatric hypoglycaemia patients.

∼25,000 scientific papers relate to ERBB-receptor signalling, in which hundreds of receptor interactions are described, forcing investigators to take a systems view of the network. Definitions ...

Financing was co-led by Forbion and General Atlantic, with participants such as RA Capital Management, OrbiMed, and Lilly ...

Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of ...