Bicycle Therapeutics plc , a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide (Bicycle®) technology, today announced that ...

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A 2009 study reported the design, construction and selection of a phage-encoded bicyclic peptide library that used a chemical linker for cyclization. This and other advanced display technologies ...

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NEP’s involvement in metabolizing natriuretic peptides, insulin, and enkephalins makes it a promising target for treating cardiovascular and Alzheimer’s diseases. Several NEP inhibitors, such as ...

Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland 4072, Australia ...

Zelenectide pevedotin is part of a new class of drugs that Bicycle calls a bicyclic toxin conjugate. It includes a bicyclic peptide designed to target Nectin-4 on the surface of cancer cells that is ...