Researchers suggest an application to FDA may be made within the next 12 months, requesting approval to carry out a human clinical trial with the gene therapy.
Human skin cells have been reprogrammed into heart valve cells and then used to ... The new procedure—which neither uses a virus as a vector nor reprograms the skin cells first into pluripotent ...
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Phase I and interim long-term follow-up study data showed that the six patients with normal left ventricular ejection fraction (LVEF ≥40%) at baseline had no evidence of heart failure ...