We transferred new genetic information into human cell lines and hematopoietic stem cells using retrovirus vectors. These vectors, containing the dominant selectable gene (neo) for resistance to ...

Increases in NKG2C Expression on T Cells and Higher Levels of Circulating CD8+ B Cells Are Associated with Sterilizing Immunity Provided by a Live Attenuated SIV Vaccine.

To further characterize the nucleoside analog susceptibility of XMRV, we determined the antiviral activities of additional NRTIs that are active against HIV-1 and other retroviruses, but that are ...

The best known of these oncoviruses – now referred to as retroviruses – is the AIDS pathogen HIV. Long before the discovery of the first human retrovirus, Schäfer suspected that such viruses can also ...

Researchers report in the journal Cell that ancient viruses may be to thank for myelin—and, by extension, our large, complex ...

Scientists have uncovered a link between ancient viral elements embedded in human DNA and the genetic risk for two major ...

For retroviruses in general, viral nucleic acids seem to access the nucleus during mitosis. In contrast, lentiviruses such as human immunodeficiency virus (HIV) do not depend on host cell mitosis ...

Human T-lymphotropic viruses, HTLV, comprise a family of four related retroviruses that affect T-cells, a type of white blood cell. The viruses are thought to have passed from monkeys into humans, and ...

Researchers at Kumamoto University have discovered a monoclonal antibody capable of neutralizing a wide range of SARS-CoV-2 ...

Retroviruses have the nifty trick of slipping a copy of their genetic instructions inside our own. More than 8% of what we think of as "human" DNA actually has such viral origins Some of these ...