The world's oceans represent a vast and largely untapped source of biodiversity, offering a high probability for the ...

"We found that the A 3 reaction was not only efficient, but also flexible enough to allow for precise control over the lipids' molecular structure," says Mitchell. This flexibility was key to fine ...

The company will develop a pipeline of small molecule inhibitors that target a unique lipid-binding pocket on proteins.

Led by Michael J. Mitchell, Associate Professor in Bioengineering, the researchers refined this delivery process by optimizing the structure of ionizable lipids. Moving beyond existing methods limited ...

Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolution. Nature Biomedical Engineering , 2024; 8 (11): 1412 DOI: 10.1038/s41551-024 ...

We found that the A3 reaction was not only efficient but also flexible enough to allow for precise control over the lipids’ molecular structure.” Michael J. Mitchell, Associate Professor ...

By improving the structure of ionizable lipids, the researchers improved this delivery method under the direction of Associate Professor of Bioengineering Michael J. Mitchell. The team created a ...

“We found that the A 3 reaction was not only efficient, but also flexible enough to allow for precise control over the lipids’ molecular structure,” says Mitchell. This flexibility was key ...