The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

This study provides a valuable look at genome-wide RNaseA-resistant RNA-DNA interactions in human embryonic stem cells. The research indicated that RNase treatment maintained long-range RNA-chromatin ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

EZH2 is also capable of methylating a number of non-histone protein substrates, such as STAT3, which promotes PD-L1 expression in tumor cells. In addition, EZH2 has a PRC2-independent role in ...

Personnel: Shixia Huang, Ph.D., Core Director, Hsin-Yi Cindy Lu, Ph.D. and Carlos Ramos, B.S., Research Staff Planning to apply to graduate school? Learn more about the BCM Graduate School of ...