Figure 3. Eat-me Signals and Don’t eat-me Signals. Upon reaching the site of injury, efferocytes encounter “eat-me” signals displayed on the membranes of apoptotic cells, initiating downstream ...

In this important study, the authors found, with the use of statistical methods, that compound heterozygous rare deletion variants affecting the kinase-domain of non-receptor tyrosine kinase TNK2/ACK1 ...

Transcription factors like Krüppel-like factor 4 (KLF4), NF-κB, specific protein-1 (SP-1), transcription factor 21 (TCF21), platelet-derived growth factor BB (PDGF-BB), and the absence of P2Y2 ...

Receptor pharmacology is the study of the interactions of receptors with drugs/pharmaceuticals and other xenobiotics. A basic tenet of receptor pharmacology is that a drug’s effect is directly ...

High-resolution microscopic images of T cells that have been engineered with TGF-beta SNIPRs (shown in red) as they bind to TGF-beta (shown in green). The SNIPRs activate once the receptors fold into ...

N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by glutamate, an excitatory neurotransmitter. These receptors are located mostly at excitatory synapses and ...