The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

Unfortunately, that has made fourth-stringer Isaac Guerendo the 49ers' starting running ... play in the critical Week 15 ...

San Francisco 49ers running back Isaac Guerendo (foot) is dealing with a foot injury, but has shown incredible potential in ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

Is Isaac Guerendo playing on "Thursday Night Football" or is he out? Is Isaac Guerendo injured or healthy for Week 15 TNF?

Three of last week’s top pickups — Isaac Guerendo (26.8 points), Adam Thielen (19.2) and Juwan Johnson (15) — won matchups in ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

With their top two options sidelined, the expectation was that rookie Isaac Guerendo would lead the backfield for the ...

The 49ers host the Rams on Thursday Night Football. They’ve been losing running backs left and right, and now we’re awaiting ...

Rams vs. 49ers at 8:20 p.m. ET/5:20 p.m. PT on Amazon Prime Video. This is it, my fellow fantasy football heads — the first ...