The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

Our fantasy football buzz file, with contributions from our ESPN fantasy writers and our NFL Nation reporters, aims to ...

San Francisco 49ers running back Isaac Guerendo (foot) is dealing with a foot injury, but has shown incredible potential in ...

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

Is Isaac Guerendo playing on "Thursday Night Football" or is he out? Is Isaac Guerendo injured or healthy for Week 15 TNF?

If the San Francisco 49ers want to defend their NFC West title, they must defeat the Los Angeles Rams in Week 15. However, the team enters Thursday Night Footba ...

The San Francisco 49ers have been decimated by injuries all year, specifically at the running back position. Christian ...

Three of last week’s top pickups — Isaac Guerendo (26.8 points), Adam Thielen (19.2) and Juwan Johnson (15) — won matchups in ...

With their top two options sidelined, the expectation was that rookie Isaac Guerendo would lead the backfield for the ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

Isaac Guerendo and Will Levis are among UPI senior sports writer Alex Butler's top fantasy football waiver wire priorities ...